ON THE CONFORMATIONAL FLEXIBILITY OF VITAMIN-D

被引：16

作者：

HOFER, O ^{[1
]}

KAHLIG, H ^{[1
]}

REISCHL, W ^{[1
]}

机构：

[1] UNIV VIENNA, INST ORGAN CHEM, A-1090 VIENNA, AUSTRIA

来源：

MONATSHEFTE FUR CHEMIE | 1993年 / 124卷 / 02期

关键词：

VITAMIN-D; FORCE-FIELD CALCULATIONS; LIS-SIMULATION; NOE-MEASUREMENTS;

D O I：

10.1007/BF00808678

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The conformational flexibility of vitamin D was investigated by a combination of force field calculations, LIS measurements and LIS simulations. Besides the two A-ring chair forms, A-ring twist forms were detected and were attributed to steric interactions arising from the substitution pattern of this class of seco-steroids.

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页码：185 / 198

页数：14

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