INVESTIGATION OF TCDD HALF-LIFE HETEROGENEITY IN VETERANS OF OPERATION RANCH HAND

被引：31

作者：

MICHALEK, JE

TRIPATHI, RC

CAUDILL, SP

PIRKLE, JL

机构：

[1] UNIV TEXAS,DIV MATH COMP SCI & STAT,SAN ANTONIO,TX 78285

[2] CTR DIS CONTROL,ATLANTA,GA 30333

来源：

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH | 1992年 / 35卷 / 01期

关键词：

D O I：

10.1080/15287399209531591

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The half-life of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the contaminant of Agent Orange, has been recently estimated in 36 members of Operation Ranch Hand, the Air Force unit responsible for the aerial spraying of Agent Orange in Vietnam, as 7.1 yr with a 90% confidence interval of 5.8-9.6 yr. We investigated the variability of TCDD half-life with percent body fat in these 36 Ranch Hand veterans who have two TCDD assay results from serum drawn in 1982 and 1987. Using a repeated measures linear model, we found a marginally significant change in half-life with percentage of body fat (p = .09) and no statistically significant change in half-life with relative changes in percentage of body fat from 1982 to 1987 (p = .60).

引用

页码：29 / 38

页数：10

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