A STUDY ON THE SCHIFF-BASE CU2ZN2SOD MODEL COMPLEXES - THE RELATIONSHIP BETWEEN STRUCTURE AND ACTIVITY

被引：25

作者：

LU, Q ^{[1
]}

SHEN, CY ^{[1
]}

LUO, QH ^{[1
]}

机构：

[1] NANJING UNIV,COORDINAT STATE KEY LAB,NANJING 210008,PEOPLES R CHINA

来源：

POLYHEDRON | 1993年 / 12卷 / 16期

关键词：

D O I：

10.1016/S0277-5387(00)81473-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

2-Acetylpyridine was condensed with NH2(CH2)nNH2 (n = 2,3,4). The di-Schiff base complexes of copper(II) were obtained for simulating superoxide dismutase. Studies on the relationship between dismutase O2- ability and coordination configuration were made. Linear relationships were obtained between E1/2 of Cu(II)L/Cu(I)L, g(parallel-to)/A(parallel-to) and catalytic activities of these complexes, respectively.

引用

页码：2005 / 2008

页数：4

共 19 条

[1] SUPEROXIDE DISMUTASE - IMPROVED ASSAYS AND AN ASSAY APPLICABLE TO ACRYLAMIDE GELS [J].

BEAUCHAM.C ;

FRIDOVIC.I .

ANALYTICAL BIOCHEMISTRY, 1971, 44 (01) :276-&

[2] SUPEROXIDE-DISMUTASE ACTIVITY OF CU(II)2(ASPIRINATE)4 AND ITS ADDUCTS WITH NITROGEN AND OXYGEN DONORS [J].

BHIRUD, RG ;

SRIVASTAVA, TS .

INORGANICA CHIMICA ACTA, 1990, 173 (01) :121-125

[3] OXYGEN-TOXICITY, OXYGEN RADICALS, TRANSITION-METALS AND DISEASE [J].

HALLIWELL, B ;

GUTTERIDGE, JMC .

BIOCHEMICAL JOURNAL, 1984, 219 (01) :1-14

[4] OXYGEN FREE-RADICALS AND IRON IN RELATION TO BIOLOGY AND MEDICINE - SOME PROBLEMS AND CONCEPTS [J].

HALLIWELL, B ;

GUTTERIDGE, JMC .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1986, 246 (02) :501-514

[5]

IBERS JA, 1980, SCIENCE, V209, P4453

[6] CATALYTIC ACTIVITY OF ETHYLENE-BRIDGED AMINO-ACID COPPER(II) COMPLEXES FOR THE DISMUTATION OF SUPEROXIDE [J].

KATZ, BM ;

STENBERG, VI .

POLYHEDRON, 1985, 4 (12) :2031-2038

[7]

KIMOTO E, 1982, CANCER RES, V43, P824

[8] ESR STUDIES ON BONDING IN COPPER COMPLEXES [J].

KIVELSON, D ;

NEIMAN, R .

JOURNAL OF CHEMICAL PHYSICS, 1961, 35 (01) :149-+

[9] THE SYNTHESIS AND CRYSTAL-STRUCTURE OF IMIDAZOLATE-BRIDGED [CU(TREN)(IM)ZN(TREN)](CLO4)3.MEOH (TREN = TRIS(2-AMINOETHYL)AMINE, IM = IMIDAZOLATE) [J].

LU, Q ;

LUO, QH ;

DAI, AB ;

ZHOU, ZY ;

HU, GZ .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1990, (20) :1429-1430

[10]

LUO QH, IN PRESS J INORG BIO

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