PERITONSILLAR INFILTRATION WITH LOW-DOSE TENOXICAM AFTER TONSILLECTOMY

被引:19
作者
KNUDSEN, KE
BROFELDT, S
MIKKELSEN, S
BILLE, M
BRENNUM, J
DAHL, JB
机构
[1] UNIV COPENHAGEN,BISPEBJERG HOSP,DEPT OTOLARYNGOL,DK-2400 COPENHAGEN,DENMARK
[2] UNIV COPENHAGEN,GLOSTRUP HOSP,DEPT NEUROL,DK-2600 GLOSTRUP,DENMARK
[3] UNIV COPENHAGEN,GLOSTRUP HOSP,DEPT ANAESTHESIOL,DK-2600 GLOSTRUP,DENMARK
关键词
PAIN; POSTOPERATIVE PAIN; ANALGESICS NONOPIOID; TENOXICAM; SURGERY; OTOLARYNGOLOGICAL;
D O I
10.1093/bja/75.3.286
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
We have compared the effect of peritonsillar infiltration with tenoxicam 5 mg and placebo on postoperative pain after tonsillectomy. Fifty patients undergoing bilateral elective tonsillectomy under general anaesthesia were allocated randomly to receive peritonsillar infiltration with tenoxicam 5 mg in 8 ml of normal saline (4 ml per tonsil) or normal saline only, before tracheal extubation. Median time to first request for morphine (30 min in each group, P = 0.83), cumulative morphine requirements from 0 to 2 h after surgery (two and one doses, P = 0.50), and from 2 to 24 h after surgery (one dose in each group, P = 0.17) were similar. There were no significant differences between groups in VAS scores at rest or when drinking 100 ml of water at any time. The power of detecting a reduction in VAS scores of 20 mm was 90% at the 5% significance level.
引用
收藏
页码:286 / 288
页数:3
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