5-[[(CARBOXYMETHYL)AMINO]METHYL]URIDINE IS FOUND IN THE ANTICODON OF YEAST MITOCHONDRIAL TRANSFER-RNAS RECOGNIZING 2-CODON FAMILIES ENDING IN A PURINE

被引：32

作者：

MARTIN, RP

SIBLER, AP

GEHRKE, CW

KUO, K

EDMONDS, CG

MCCLOSKEY, JA

DIRHEIMER, G

机构：

[1] UNIV STRASBOURG 1,F-67084 STRASBOURG,FRANCE

[2] CANC RES CTR,COLUMBIA,MO 65201

[3] UNIV MISSOURI,DEPT BIOCHEM,COLUMBIA,MO 65211

[4] UNIV UTAH,DEPT MED CHEM,SALT LAKE CITY,UT 84112

来源：

BIOCHEMISTRY | 1990年 / 29卷 / 04期

关键词：

D O I：

10.1021/bi00456a016

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The modified nucleoside (U*) present in the wobble position of Saccharomyces cerevisiae mitochondrial tRNALeu and tRNATrp was isolated by thin-layer chromatography and HPLC. Its chromatographic, UV spectral, and mass spectrometric properties were shown to be identical with those of 5-[[(carboxymethyl)amino]methyl]uridine (cmnm5U). This nucleoside found in yeast mitochondrial tRNAs reading two-codon families ending in a purine permits the selective recognition of A and G in the third codon position. © 1990, American Chemical Society. All rights reserved.

引用

页码：956 / 959

页数：4

共 22 条

[1]

BJORK GR, 1984, PROCESSING RNA, P291

[2]

BUCK M, 1983, ANAL BIOCHEM, V129, P1, DOI 10.1016/0003-2697(83)90044-1

[3]

DIRHEIMER G, 1990, IN PRESS ELSEVIER CH, V2

[4]

DIRHEIMER G, 1983, RECENT RES CANCER, V84, P1

[5] THERMOSPRAY LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY OF NUCLEOSIDES AND OF ENZYMATIC HYDROLYSATES OF NUCLEIC-ACIDS [J].

EDMONDS, CG ;

VESTAL, ML ;

MCCLOSKEY, JA .

NUCLEIC ACIDS RESEARCH, 1985, 13 (22) :8197-8206

[6] RIBONUCLEOSIDE ANALYSIS BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

GEHRKE, CW ;

KUO, KC .

JOURNAL OF CHROMATOGRAPHY, 1989, 471 :3-36

[7] QUANTITATIVE ENZYMATIC-HYDROLYSIS OF TRANSFER-RNAS - REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF TRANSFER-RNA NUCLEOSIDES [J].

GEHRKE, CW ;

KUO, KC ;

MCCUNE, RA ;

GERHARDT, KO ;

AGRIS, PF .

JOURNAL OF CHROMATOGRAPHY, 1982, 230 (02) :297-308

[8]

GEHRKE CW, 1990, IN PRESS ELSEVIER CH, V1

[9]

HAGERVALL TG, 1987, J BIOL CHEM, V262, P8488

[10] NOVEL FEATURES IN THE GENETIC-CODE AND CODON READING PATTERNS IN NEUROSPORA-CRASSA MITOCHONDRIA BASED ON SEQUENCES OF 6 MITOCHONDRIAL TRANSFER-RNAS [J].

HECKMAN, JE ;

SARNOFF, J ;

ALZNERDEWEERD, B ;

YIN, S ;

RAJBHANDARY, UL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (06) :3159-3163

← 1 2 3 →