IDENTIFICATION OF THE MAIN METABOLITE OF ETHYLENETHIOUREA IN MICE

被引：10

作者：

SAVOLAINEN, K

PYYSALO, H

机构：

[1] Technical Research Centre of Finland, Food Research Laboratory, Espoo 15, Biologinkuja 1

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 1979年 / 27卷 / 06期

关键词：

D O I：

10.1021/jf60226a006

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

The degradation of 2-imidazolidinethione (ethylenethiourea) in mice involves oxidation at the sulfur atom, giving 2-imidazolin-2-yl sulfenate as the major product. This compound was synthesized by irradiation of an aqueous solution of ethylenethiourea with Co-60 γ rays and purified from the irradiation mixture by high-pressure liquid chromatography. The synthesis was verified by TLC, IR, NMR, and mass spectrometry methods. Otherpossible mechanisms for degradation are discussed. © 1979, American Chemical Society. All rights reserved.

引用

页码：1177 / 1181

页数：5

共 26 条

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