DYNAMIC CARDIOMYOPLASTY FOR LONG-TERM CARDIAC ASSIST

被引:28
作者
CHACHQUES, JC
ACAR, C
PORTOGHESE, M
BENSASSON, D
GUIBOURT, P
GRARE, P
JEBARA, VA
GRANDJEAN, PA
CARPENTIER, A
HAGL, S
MIKAELOFF, P
机构
[1] Service de Chirurgie Cardiovasculaire, Hôpital Broussais, Paris, F-75014
关键词
CARDIOMYOPLASTY; CONGESTIVE HEART FAILURE; CARDIAC ASSIST; LATISSIMUS DORSI MUSCLE; ELECTROPHYSIOLOGY;
D O I
10.1016/1010-7940(92)90188-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The principle of cardiomyoplasty is long-term electrostimulation of a latissimus dorsi muscle (LDM) wrapped around the failing heart. Technically, this procedure consists of placing the left LDM flap around the heart via a window created by partial resection of the 2nd or 3rd rib, and subsequent muscle electrostimulation in synchrony with ventricular systole. The aim of cardiomyoplasty is to support ventricular function in ischemic or dilated cardiomyopathies, or to partially replace the ventricular myocardium after large aneurysm or tumor resections. Our clinical experience at Broussais Hospital involves 44 patients. The functional class and quality of life improved after cardiomyoplasty. Improvement of the ventricular performance and limitation of cardiac dilatation were demonstrated over the long-term. The actuarial survival at 6 years was 71 %. Risk factors influencing perioperative mortality were: age > 65 years, associated surgical procedures, pulmonary vascular hypertension, and patients hemodynamically unstable or on inotropic drug support. Preoperative risk factors influencing the long-term mortality were: permanent NYHA functional class 4, cardiothoracic ratio > 0.60, LV ejection fraction < 15 %, bi-ventricular heart failure, and atrial fibrillation. Cardiomyoplasty does not preclude the use of future orthotopic heart transplantation.
引用
收藏
页码:642 / 648
页数:7
相关论文
共 23 条
[1]  
Carpentier A., Chachques J.C., Myocardial substitution with a stimulated skeletal muscle: First successful clinical case, Lancet, 1, (1985)
[2]  
Carpentier A., Chachques J.C., Grandjean P.A., Perier P., Mitz V., Bourgeois I., Transformation d‘un muscle squelettique par stimulation séquentielle progressive en vue de son utilisation comme substitut myocardique, C R Acad Sei [III], 301, pp. 581-586, (1985)
[3]  
Carpentier A., Chachques J.C., Grandjean P.A., Car-diomyoplasty, pp. 1-280, (1991)
[4]  
Chachques J.C., Grandjean P.A., Smits K., Cardio-myostimulator: Method and apparatus including a sliding insulation lead for cardiac assistance, European Patent 0, 234, 457, (1987)
[5]  
Chachques J.C., Grandjean P., Schwartz K., Mihaileanu S., Fardeau M., Swynghedauw B., Fontaliran F., Romero N., Wis-newsky C., Perier P., Chauvaud S., Bourgeois I., Carpentier A., Effect of latissimus dorsi dynamic cardiomyoplasty on ventricular function, Circulation, 78, pp. 203-216, (1987)
[6]  
Chachques J.C., Grandjean P.A., Carpentier A., Latissimus dorsi dynamic cardiomyoplasty, Ann Thorac Surg, 47, pp. 600-604, (1989)
[7]  
Chachques J.C., Grandjean P.A., Perier P., Nataf P., Acar C., Mihaileanu S., Bensasson D., Kieffer J.P., Abry B., Fabiani J.N., Deloche A., Blondeau P., Carpentier A., Cardiomyoplastie: Bases expérimentales, technique opératoire, indications, Arch Mal Coeur, 82, pp. 919-926, (1989)
[8]  
Chachques J.C., Grandjean P., Serraf A., Latremouiiie C., Jebara V.A., Ponzio O., Mihaileanu S., Chauvaud S., Bourgeois I., Carpentier A., Atrial cardiomyoplasty after Fontan-type procedures, Circulation, 82, pp. 183-189, (1990)
[9]  
Chachques J.C., Grandjean P.A., Carpentier A., Patient management and clinical follow-up after cardiomyoplasty, J Cardiac Surg, 6, pp. 89-99, (1991)
[10]  
Delahaye F., Jegaden O., Montagna P., Desseigne P., Blanc P., Vedrinne C., Touboul P., Saint-Pierre A., Perinetti M., Rossi R., Itti R., Mikaeloff P., Latissimus dorsi cardiomyoplasty in severe congestive heart failure: The Lyon experience, J Cardiac Surg, 6, pp. 106-112, (1991)