GROWTH IN CHILDREN WITH THALASSAEMIA MAJOR AND EFFECT OF 2 DIFFERENT TRANSFUSION REGIMENS

被引：25

作者：

BROOK, CGD

THOMPSON, EN

MARSHALL, WC

WHITEHOUSE, RH

机构：

[1] Hospital for Sick Children, Great Ormond Street

[2] Institute of Child Health, University of London, London W.C.1

[3] Department of Child Health, Welsh National School of Medicine, Cardiff

来源：

ARCHIVES OF DISEASE IN CHILDHOOD | 1969年 / 44卷 / 237期

关键词：

D O I：

10.1136/adc.44.237.612

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Longitudinal data on height, growth, and skeletal maturation on 28 children with thalassaemia major are reported. Prepubertal growth and skeletal maturity were within normal limits, but in 3 children where puberty would have been expected, it appeared to be delayed. In 20 children, in whom a comparison of height velocity before and after a high-level transfusion regimen was possible, the latter was associated with a significant depression of prepubertal growth. So far as growth is concerned, high-level transfusion is of no advantage and may be deleterious.

引用

页码：612 / +

页数：1