PROTEOGLYCAN EPITOPE IN SYNOVIAL-FLUID IN GONARTHROSIS - 28 CASES OF TIBIAL OSTEOTOMY STUDIED PROSPECTIVELY FOR 2 YEARS

被引:8
作者
ODENBRING, S [1 ]
EGUND, N [1 ]
LINDSTRAND, A [1 ]
LOHMANDER, LS [1 ]
机构
[1] UNIV LUND HOSP,DEPT DIAGNOST RADIOL,S-22185 LUND,SWEDEN
来源
ACTA ORTHOPAEDICA SCANDINAVICA | 1991年 / 62卷 / 02期
关键词
D O I
10.3109/17453679108999250
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
High tibial osteotomy was performed for medial gonarthrosis in 28 patients. Preoperatively, and at 3, 12, and 24 months after surgery, clinical and radiographic examinations were made, and joint-fluid samples were aspirated. Arthroscopy was performed preoperatively and at 24 months. Immunoassay of proteoglycan epitope in joint fluid showed an increase in concentration at all times as compared with a reference population with normal knee joints. An increase in both the concentration and the total amount of proteoglycan epitope in joint fluid was noted at 3 months postoperatively with a return to preoperative values at later times. Regrowth of fibrocartilage did not correlate with proteoglycan epitope data.
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页码:169 / 173
页数:5
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