N-BROMOSUCCINIMIDE DIBROMODIMETHYLHYDANTOIN IN AQUEOUS BASE - A PRACTICAL METHOD FOR THE BROMINATION OF ACTIVATED BENZOIC-ACIDS

被引：93

作者：

AUERBACH, J

WEISSMAN, SA

BLACKLOCK, TJ

ANGELES, MR

HOOGSTEEN, K

机构：

[1] Merck Manufacturing Division Merck, Co., Inc., Rahway, NJ 07065

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 06期

关键词：

D O I：

10.1016/S0040-4039(00)77457-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new bromination method employing NBS or dibromodimethylhydantoin in aqueous base is described for the synthesis of 3-bromo-2,6-dimethoxybenzoic acid (1) and other monobrominated alkoxybenzoic acids.

引用

页码：931 / 934

页数：4

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