A PRODUCT FROM REACTION OF PYRIDINE WITH ACETIC ANHYDRIDE

被引：9

作者：

FLEMING, I

MASON, JB

机构：

[1] University Chemical Laboratory, Cambridge

[2] Dunn Nutritional Laboratory, University of Cambridge, Medical Research Council, Cambridge

来源：

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1969年 / 18期

关键词：

D O I：

10.1039/j39690002509

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A crystalline product obtained from an attempted acetylation with pyridine and acetic anhydride (in the presence of a niacytin hydrolysate) is shown to be N-acetyl-1,2-dihydro-2-pyridylacetic acid (1), produced by combination of the pyridine and the acetic anhydride.

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页码：2509 / &

相关论文

共 18 条

[1]

BAILEY AS, 1968, TETRAHEDRON LETT, P5953

[2] THE REACTION OF BENZYLMAGNESIUM CHLORIDE AND DIBENZYLMAGNESIUM WITH PYRIDINE [J].

BENKESER, RA ;

HOLTON, DS .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1951, 73 (12) :5861-5862

[3] The preparation of 2-alkyl and 2-aryl pyridines and quinolines by the Grignard reaction (preliminary) [J].

Bergstrom, FW ;

McAllister, SH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1930, 52 :2845-2849

[4] PERICYCLIC REACTIONS .I. AN EXAMINATION OF SOME POTENTIALLY PERICYCLIC REACTIONS IN MASS SPECTROMETER [J].

BISHOP, MJ ;

FLEMING, I .

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1969, (13) :1712-&

[5] CONDENSATION OF KETONES WITH ACYLPYRIDINIUM SALTS [J].

DOERING, WV ;

MCEWEN, WE .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1951, 73 (05) :2104-2109

[6] MECHANISM OF THE DECARBOXYLATION OF ALPHA-PYRIDYLACETIC ACID [J].

DOERING, WV ;

PASTERNAK, VZ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1950, 72 (01) :143-147

[7] ACETYLPYRIDINIUM ION INTERMEDIATE IN PYRIDINE-CATALYZED ACYL TRANSFER [J].

FERSHT, AR ;

JENCKS, WP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1969, 91 (08) :2125-+

[8]

Giam C. S., 1969, CHEM COMMUN, P142

[9] REINVESTIGATION OF THE REACTION OF ETHYLMAGNESIUM BROMIDE WITH PYRIDINE [J].

GOETZLUTHY, N .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1949, 71 (06) :2254-2255

[10]

KODICEK E, 1960, BIOCHEM J, V76, pP27