DEVELOPMENT OF RECOMBINANT HIRUDIN AS A THERAPEUTIC ANTICOAGULANT AND ANTITHROMBOTIC AGENT - SOME OBJECTIVE CONSIDERATIONS

被引：45

作者：

WALENGA, JM

PIFARRE, R

HOPPENSTEADT, DA

FAREED, J

机构：

[1] LOYOLA UNIV, MED CTR, DEPT THORAC & CARDIOVASC SURG, MAYWOOD, IL 60153 USA

[2] LOYOLA UNIV, MED CTR, DEPT PHARMACOL, MAYWOOD, IL 60153 USA

来源：

SEMINARS IN THROMBOSIS AND HEMOSTASIS | 1989年 / 15卷 / 03期

关键词：

D O I：

10.1055/s-2007-1002724

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：316 / 333

页数：18

共 63 条

[1]

BAGDY D, 1973, Thrombosis Research, V2, P229, DOI 10.1016/0049-3848(73)90086-8

[2]

BAGDY O, 1976, METHOD ENZYMOL, V45, P669

[3]

Baskova I P, 1980, Biokhimiia, V45, P267

[4] CHEMICAL SYNTHESIS AND EXPRESSION OF A GENE CODING FOR HIRUDIN, THE THROMBIN-SPECIFIC INHIBITOR FROM THE LEECH HIRUDO-MEDICINALIS [J].

BERGMANN, C ;

DODT, J ;

KOHLER, S ;

FINK, E ;

GASSEN, HG .

BIOLOGICAL CHEMISTRY HOPPE-SEYLER, 1986, 367 (08) :731-740

[5]

BICHLER J, 1988, ARZNEIMITTEL-FORSCH, V38-1, P704

[6] A COMPARISON OF THE ANTITHROMBOTIC AND HEMORRHAGIC EFFECTS OF LOW-MOLECULAR WEIGHT HEPARIN FRACTIONS - THE INFLUENCE OF THE METHOD OF PREPARATION [J].

CADE, JF ;

BUCHANAN, MR ;

BONEU, B ;

OCKELFORD, P ;

CARTER, CJ ;

CERSKUS, AL ;

HIRSH, J .

THROMBOSIS RESEARCH, 1984, 35 (06) :613-625

[7] EFFECT OF HIRUDIN A POTENT ANTITHROMBIN ON THROMBOPLASTIN GENERATION TEST [J].

CALDWELL, MJ .

THROMBOSIS ET DIATHESIS HAEMORRHAGICA, 1967, 17 (1-2) :256-&

[8] THE FUNCTIONAL DOMAIN OF HIRUDIN, A THROMBIN-SPECIFIC INHIBITOR [J].

CHANG, JY .

FEBS LETTERS, 1983, 164 (02) :307-313

[9]

COURTNEY M, 1987, THROMB RES S, V30

[10] ISOLATION AND CHARACTERIZATION OF HIRUDIN ISOINHIBITORS AND SEQUENCE-ANALYSIS OF HIRUDIN-PA [J].

DODT, J ;

MACHLEIDT, W ;

SEEMULLER, U ;

MASCHLER, R ;

FRITZ, H .

BIOLOGICAL CHEMISTRY HOPPE-SEYLER, 1986, 367 (08) :803-811

← 1 2 3 4 5 6 7 →