SIMULTANEOUS EXTRACTION AND DETERMINATION OF SULFADIAZINE AND TRIMETHOPRIM IN MEDICATED FISH FEED BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引：12

作者：

HORMAZABAL, V ^{[1
]}

STEFFENAK, I ^{[1
]}

YNDESTAD, M ^{[1
]}

机构：

[1] NORWEGIAN COLL VET MED,DEPT FOOD HYG,POB 8146 DEP,N-0033 OSLO 1,NORWAY

来源：

JOURNAL OF CHROMATOGRAPHY | 1993年 / 648卷 / 01期

关键词：

D O I：

10.1016/0021-9673(93)83300-H

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A simple and rapid method for the simultaneous extraction and determination of sulfadiazine and trimethoprim in medicated fish feed by HPLC using sulfadimidine as internal standard is presented. The calibration curves were linear in the investigated areas, 1.25-10 mg/g of sulfadiazine and 0.25-2 mg/g trimethoprim. The recovery of sulfadiazine was 96-99%, and the recovery of trimethoprim 100-105%.

引用

页码：183 / 186

页数：4

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