Characterization of two biodegradable polymers of potential application within the biomaterials field

被引:84
作者
Reis, RL
Cunha, AM
机构
[1] INEB, INST BIOMED ENGN, P-4050 OPORTO, PORTUGAL
[2] UNIV MINHO, DEPT POLYMER ENGN, DEP, P-4800 GUIMARAES, PORTUGAL
关键词
D O I
10.1007/BF00134318
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
An extensive characterization of two biodegradable polymers that may constitute an alternative, if one is aiming at orthopaedic applications, to the currently used poly(glicolic acid), poly(lactic acid) or polyhydroxybutyrate was carried out. A cellulose acetate and three different grades of a novel starch based polymer were studied. The characterization included: tensile and instrumented impact tests, theological measurements, scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier transformed infra-red spectroscopy (FTIR), differential scanning calorimetry (DSC), and long-term degradation trials in Hank's solution. The results show that both polymers, specially the starch based one, present a great potential for biomedical applications, on which adequate mechanical properties associated to a controlled degradation rate are required.
引用
收藏
页码:786 / 792
页数:7
相关论文
共 17 条
[1]  
Knowles J.C., Hastings G.W., J. Mater. Sci.: Mater. in Medicine, 3, (1992)
[2]  
Langer R.S., Peppas N.A., Biomaterials, 2, (1981)
[3]  
Capperauld I., Clin. Mater., 4, (1989)
[4]  
Hayashi T., Prog. Polym. Sci., 19, (1994)
[5]  
Tormala P., Clin. Mater., 13, (1993)
[6]  
Andriano K.P., Pohjonen T., Tormala P., J. Apl. Biomater., 5, (1994)
[7]  
Knowles J.C., Hastings G.W., J. Mater. Sci.: Mater. in Medicine, 4, (1993)
[8]  
Rokkanen P.U., Ann. Med., 23, (1991)
[9]  
Danniels A.U., Andriano K.P., Smutz W.P., Chang M.K.O., Heller J., Evaluation of absorbable poly(ortho esters) for use in surgical implants, Journal of Applied Biomaterials, 5, (1994)
[10]  
Terjesen T., Apalest K., J. Orthop. Res., 6, (1988)