RISK OF ANOTHER BASAL-CELL CARCINOMA DEVELOPING AFTER TREATMENT OF A BASAL-CELL CARCINOMA

被引:76
作者
MARGHOOB, A [1 ]
KOPF, AW [1 ]
BART, RS [1 ]
SANFILIPPO, L [1 ]
SILVERMAN, MK [1 ]
LEE, P [1 ]
LEVY, E [1 ]
VOSSAERT, KA [1 ]
YADAV, S [1 ]
ABADIR, M [1 ]
机构
[1] NYU MED CTR,ONCOL SECT,NEW YORK,NY 10016
关键词
D O I
10.1016/0190-9622(93)70003-C
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background: There is an increased risk of new basal cell carcinomas (BCCs) developing in a person who has had a BCC. Objective: This study attempts to define the magnitude of this increased risk. Methods: The charts of 260 white patients with a histologically proven BCC were reviewed for the occurrence of new BCCs. The cumulative 5-year incidence (modified life-table method) for new BCCs developing in these patients was compared with the 5-year incidence in the general white population of the United States. Results: Of the 260 patients, new BCCs developed in 137 within an average of 38.3 months, a 5-year cumulative rate of one or more new BCCs of 45.2%. The yearly risk for new BCCS developing in the study population remained high during the 5-year interval. In the general white population of the United States, the maximal 5-year incidence was calculated to be 5% (p < 0.005, chi-square test). Conclusion: Patients with a history of BCC require life-long follow-up because of the high probability of new BCCs developing.
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页码:22 / 28
页数:7
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