HEPARIN-SURFACE-MODIFIED INTRAOCULAR-LENS IMPLANTATION IN EYES WITH PSEUDOEXFOLIATION SYNDROME

被引:22
作者
RAVALICO, G
TOGNETTO, D
BACCARA, F
机构
[1] Eye Clinic, University of Trieste
关键词
BLOOD AQUEOUS BARRIER; FLUOROPHOTOMETRY; HEPARIN-SURFACE-MODIFIED INTRAOCULAR LENS; IRIS ANGIOGRAPHY; PSEUDOEXFOLIATION SYNDROME;
D O I
10.1016/S0886-3350(13)80235-0
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Eyes with pseudoexfoliation syndrome have a greater risk of intraoperative and postoperative complications. Clinical and histopathological studies indicate that heparin-surface-modified intraocular lenses (HSM IOLs) can reduce postoperative anterior segment inflammation. Our study evaluated the blood-aqueous barrier permeability in eyes with pseudoexfoliation syndrome and implanted with an HSM IOL. We examined two groups of 20 patients, one comprising patients with pseudoexfoliation syndrome and one a sex- and age-matched control group with senile cataracts. Each group was divided into two subgroups of ten patients each. In one subgroup, an HSM IOL was implanted; in the other, a conventional poly(methyl methacrylate) IOL. We performed a complete ophthalmologic examination and iris angiography preoperatively and at 30, 90, and 180 days after surgery. Fluorophotometry was performed at the 90-day and 180-day postoperative examinations. The patients with pseudoexfoliation syndrome had a higher blood-aqueous barrier permeability than did the control group. Permeability decreased significantly three and six months after surgery, especially in the HSM IOL group.
引用
收藏
页码:543 / 549
页数:7
相关论文
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