SUPPURATIVE CUTANEOUS GRANULOMATA CAUSED BY MICROASCUS-CINEREUS IN A PATIENT WITH CHRONIC GRANULOMATOUS-DISEASE

被引:21
作者
MARQUES, AR
KWONCHUNG, KJ
HOLLAND, SM
TURNER, ML
GALLIN, JI
机构
[1] NIAID,HOST DEF LAB,BETHESDA,MD 20892
[2] NIAID,CLIN INVEST LAB,BETHESDA,MD 20892
[3] NCI,DERMATOL BRANCH,BETHESDA,MD 20892
基金
美国国家卫生研究院;
关键词
D O I
10.1093/clinids/20.1.110
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We describe a patient with chronic granulomatous disease who presented with erythematous papular skin lesions on the chest, back, and arm, Examination of biopsy specimens from the lesions on the arm and back showed suppurative granulomata in association with acute and chronic inflammation, Histopathologic examination of a specimen from the lesion on the arm revealed fungal elements, and cultures yielded Microascus cinereus. The patient was treated with 2.5 g of intravenous amphotericin B, and the lesions resolved. We report what is, to our knowledge, the first case of invasive disease due solely to M, cinereus.
引用
收藏
页码:110 / 114
页数:5
相关论文
共 29 条
  • [1] Agarwal G P, 1980, Indian J Med Sci, V34, P263
  • [2] MAXILLARY SINUSITIS FROM MICROASCUS-CINEREUS AND ASPERGILLUS-REPENS
    AZNAR, C
    DEBIEVRE, C
    GUIGUEN, C
    [J]. MYCOPATHOLOGIA, 1989, 105 (02) : 93 - 97
  • [3] BARRON G. L., 1961, CANADIAN JOUR BOT, V39, P1609, DOI 10.1139/b61-143
  • [4] BOLTANSKY H, 1984, J INFECT DIS, V149, P653, DOI 10.1093/infdis/149.4.653
  • [5] FUNGAL INFECTION IN CHRONIC GRANULOMATOUS-DISEASE - THE IMPORTANCE OF THE PHAGOCYTE IN DEFENSE AGAINST FUNGI
    COHEN, MS
    ISTURIZ, RE
    MALECH, HL
    ROOT, RK
    WILFERT, CM
    GUTMAN, L
    BUCKLEY, RH
    [J]. AMERICAN JOURNAL OF MEDICINE, 1981, 71 (01) : 59 - 66
  • [6] CUTANEOUS RINGWORM LESIONS OF SCOPULARIOPSIS-BREVICAULIS
    COX, NH
    IRVING, B
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 1993, 129 (06) : 726 - 728
  • [7] DEVROEY C, 1993, MYMYCOSES, V35, P193
  • [8] SCOPULARIOPSIS-BREVICAULIS SKIN-LESIONS IN AN AIDS PATIENT
    DHAR, J
    CAREY, PB
    [J]. AIDS, 1993, 7 (09) : 1283 - 1284
  • [9] Emile-Weil P, 1919, ARCH MED EXP ANAT PA, V28, P452
  • [10] THE PERFECT STAGE OF HORMODENDRUM PEDROSOI
    FUENTES, CA
    WOLF, FA
    [J]. MYCOLOGIA, 1956, 48 (01) : 56 - 64