FUNCTIONAL-ROLE OF PROTEOLYTIC CLEAVAGE AT ARGININE-275 OF HUMAN-TISSUE PLASMINOGEN-ACTIVATOR AS ASSESSED BY SITE-DIRECTED MUTAGENESIS

被引：140

作者：

TATE, KM ^{[1
]}

HIGGINS, DL ^{[1
]}

HOLMES, WE ^{[1
]}

WINKLER, ME ^{[1
]}

HEYNEKER, HL ^{[1
]}

VEHAR, GA ^{[1
]}

机构：

[1] GENENTECH INC,DEPT MOLEC BIOL & BIOCHEM,S SAN FRANCISCO,CA 94080

来源：

BIOCHEMISTRY | 1987年 / 26卷 / 02期

关键词：

D O I：

10.1021/bi00376a002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

收藏

页码：338 / 343

页数：6

相关论文

共 40 条

[1] ADELMAN JP, 1983, DNA, V2, P83
[2] INACTIVE PROENZYME TO TISSUE-TYPE PLASMINOGEN-ACTIVATOR FROM HUMAN-MELANOMA CELLS, IDENTIFIED AFTER AFFINITY PURIFICATION WITH A MONOCLONAL-ANTIBODY
ANDREASEN, PA
NIELSEN, LS
GRONDAHLHANSEN, J
SKRIVER, L
ZEUTHEN, J
STEPHENS, RW
DANO, K
[J]. EMBO JOURNAL, 1984, 3 (01) : 51 - 56
[3] EVIDENCE FOR A RAPID INHIBITOR TO TISSUE PLASMINOGEN-ACTIVATOR IN PLASMA
CHMIELEWSKA, J
RANBY, M
WIMAN, B
[J]. THROMBOSIS RESEARCH, 1983, 31 (03) : 427 - 436
[4] COLLEN D, 1980, THROMB HAEMOSTASIS, V43, P77
[5] PLASMINOGEN - PURIFICATION FROM HUMAN PLASMA BY AFFINITY CHROMATOGRAPHY
DEUTSCH, DG
MERTZ, ET
[J]. SCIENCE, 1970, 170 (3962) : 1095 - +
[6] ESTELL DA, 1985, J BIOL CHEM, V260, P6518
[7] CHYMOTRYPSINOGEN - 2.5-A CRYSTAL STRUCTURE, COMPARISON WITH ALPHA-CHYMOTRYPSIN, AND IMPLICATIONS FOR ZYMOGEN ACTIVATION
FREER, ST
KRAUT, J
ROBERTUS, JD
WRIGHT, HT
XUONG, NH
[J]. BIOCHEMISTRY, 1970, 9 (09) : 1997 - &
[8] FUCHS HE, 1985, BLOOD, V65, P539
[9] GOEDDEL DV, 1983, Patent No. 2119804
[10] INHIBITION OF THE HUMAN-TISSUE PLASMINOGEN-ACTIVATOR IN PLASMA FROM DIFFERENT SPECIES
HAGGROTH, L
MATTSSON, C
FRIBERG, J
[J]. THROMBOSIS RESEARCH, 1984, 33 (06) : 583 - 594

← 1 2 3 4 →