A RAPID AND ROBUST PARTICLE-ENHANCED TURBIDIMETRIC IMMUNOASSAY FOR SERUM BETA-2 MICROGLOBULIN

被引：27

作者：

MEDCALF, EA

NEWMAN, DJ

GILBOA, A

GORMAN, EG

PRICE, CP

机构：

[1] UNIV LONDON LONDON HOSP,COLL MED,DEPT CLIN BIOCHEM,TURNER ST,LONDON E1 2AD,ENGLAND

[2] DUPONT CO,WILMINGTON,DE 19898

来源：

JOURNAL OF IMMUNOLOGICAL METHODS | 1990年 / 129卷 / 01期

关键词：

Calibration stability; Particle-enhanced turbidimetric immunoassay; Serum β[!sub]2[!/sub] microglobulin;

D O I：

10.1016/0022-1759(90)90425-U

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A rapid particle-enhanced turbidimetric immunoassay (PETIA), for the measurement of serum β2-microglobulin is described. The method has a working range of 0.2-40 mg/l, with good precision and a correlation coefficient of 0.97 when compared with an established radioimmunoassay method. One of the major advantages of this assay is the stability of the calibration curve (up to at least 20 months). This, and the fact that no pretreatment of serum samples is necessary, makes the assay ideally suited for all types of routine determination. © 1990.

引用

页码：97 / 103

页数：7

共 19 条

[1]

BERGGARD I, 1968, J BIOL CHEM, V243, P4095

[2]

BERNARD AM, 1981, CLIN CHEM, V27, P832

[3] MEASUREMENT OF BETA-2-MICROGLOBULIN IN SERUM AND PLASMA BY AN ENZYME-LINKED-IMMUNOSORBENT-ASSAY (ELISA) [J].