UNUSUAL SERPENTINE HYPERPIGMENTATION ASSOCIATED WITH 5-FLUOROURACIL - CASE-REPORT AND REVIEW OF CUTANEOUS MANIFESTATIONS ASSOCIATED WITH SYSTEMIC 5-FLUOROURACIL

被引：31

作者：

VUKELJA, SJ ^{[1
]}

BONNER, MW ^{[1
]}

MCCOLLOUGH, M ^{[1
]}

COBB, PW ^{[1
]}

GAULE, DA ^{[1
]}

FANUCCHI, PJ ^{[1
]}

KEELING, JH ^{[1
]}

机构：

[1] BROOKE ARMY MED CTR, DEPT MED, DERMATOL SERV, FT SAM HOUSTON, TX 78234 USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 1991年 / 25卷 / 05期

关键词：

D O I：

10.1016/0190-9622(91)70280-F

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

A variety of cutaneous reactions have been reported with the use of systemic 5-fluorouracil. Our patient had serpentine hyperpigmented streaks appearing 5 days after bolus infusion of 5-fluorouracil. The patient also had other skin eruptions, that is, inflammation of actinic keratoses and folliculitis limited to the forehead; these reactions have been reported previously with 5-fluorouracil medication. We report this case and review the literature on skin manifestations associated with 5-fluorouracil therapy.

引用

页码：905 / 908

页数：4

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