SYNTHESIS OF 3-HALOMETHYL-2,3,4,5-TETRAHYDRO-2,5-METHANO-1H-2-BENZAZEPINES AND THEIR REARRANGEMENT TO 4-HALO-1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-2-BENZAZOCINES

被引：15

作者：

BLOUGH, BE

MASCARELLA, SW

ROTHMAN, RB

CARROLL, FI

机构：

[1] RES TRIANGLE INST,POB 12194,RES TRIANGLE PK,NC 27709

[2] NIDA,ADDICT RES CTR,CLIN PSYCHOPHARMACOL SECT,BALTIMORE,MD 21224

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1993年 / 09期

关键词：

D O I：

10.1039/c39930000758

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This study reports a three-step synthesis of 3-halomethyl-2,3,4,5-tetrahydro-2,5-methano-1 H-2-benzazepines 2a-c and the rearrangement of 2a-b to 4-iodo- and 4-bromo-1,2,3,4,5,6-hexahydro-2,6-methano-2-methano-2-benzazocines 1a-b.

引用

页码：758 / 760

页数：3

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