STRUCTURE OF CHELERYTHRINE BASE

被引：39

作者：

DOSTAL, J

TABORSKA, E

SLAVIK, J

POTACEK, M

DEHOFFMANN, E

机构：

[1] MASARYK UNIV,FAC SCI,DEPT ORGAN CHEM,CS-61137 BRNO,CZECH REPUBLIC

[2] UNIV CATHOLIQUE LOUVAIN,MASS SPECTROSCOPY LAB,B-1348 LOUVAIN,BELGIUM

来源：

JOURNAL OF NATURAL PRODUCTS-LLOYDIA | 1995年 / 58卷 / 05期

关键词：

D O I：

10.1021/np50119a010

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The structure of chelerythrine free base was examined. When chelerythrine chloride [1b] was treated with aqueous K2CO3 solution, bis[6-(5,6-dihydrochelerythrinyl)] ether [3] was obtained. An excess of aqueous ammonia under the same conditions yielded bis[6-(5,6-dihydrochelerythrinyl)] amine [4]. The structures of both derivatives were determined by elemental analysis, ir, 1D and 2D nmr, eims, and cims. The formation of an unstable hydroxy adduce 2a (pseudobase) was observed in H-1-nmr experiments only.

引用

页码：723 / 729

页数：7

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