SPECTRUM OF ACTIVITY OF SOLUBLE INTERCELLULAR-ADHESION MOLECULE-1 AGAINST RHINOVIRUS REFERENCE STRAINS AND FIELD ISOLATES

被引：25

作者：

OHLIN, A

HOOVERLITTY, H

SANDERSON, G

PAESSENS, A

JOHNSTON, SL

HOLGATE, ST

HUGUENEL, E

GREVE, JM

机构：

[1] MILES BIOTECHNOL,INST INFLAMMAT & EXPTL MED,W HAVEN,CT 06516

[2] MILES BIOTECHNOL,INST MOLEC BIOL,W HAVEN,CT 06516

[3] UNIV SOUTHAMPTON,SOUTHAMPTON GEN HOSP,IMMUNOPHARMACOL GRP,SOUTHAMPTON S09 4XY,ENGLAND

[4] PHARMA RES CTR,INST VIROL,D-42096 WUPPERTAL,GERMANY

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1994年 / 38卷 / 06期

关键词：

D O I：

10.1128/AAC.38.6.1413

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The antiviral potency of soluble intercellular adhesion molecule-1 (IDAM-1; the major receptor for human rhinoviruses) was determined for a subset of American Type Culture Collection reference serotypes and held isolates of rhinovirus. The results indicate that soluble ICAM-1 exhibits a broad spectrum of activity against rhinoviruses and that field isolates have a sensitivity indistinguishable from that of laboratory strains.

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页码：1413 / 1415

页数：3

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