THE SCHIZOSACCHAROMYCES-POMBE-RAD1 GENE CONSISTS OF 3 EXONS AND THE CDNA SEQUENCE IS PARTIALLY HOMOLOGOUS TO THE USTILAGO-MAYDIS-REC1 CDNA

被引：25

作者：

LONG, KE ^{[1
]}

SUNNERHAGEN, P ^{[1
]}

SUBRAMANI, S ^{[1
]}

机构：

[1] UNIV CALIF SAN DIEGO, DEPT BIOL, LA JOLLA, CA 92093 USA

来源：

GENE | 1994年 / 148卷 / 01期

关键词：

NUCLEOTIDE SEQUENCE; DNA REPAIR; CELL CYCLE CHECKPOINTS; PCR; RADIATION RESISTANCE;

D O I：

10.1016/0378-1119(94)90250-X

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We show that the rad1 gene of Schizosaccharomyces pombe is comprised of three exons and encodes a protein of 37 kDa. A cDNA clone containing these three exons complements the sensitivity of the rad1-1 mutant to ultraviolet and gamma-radiation and to hydroxyurea. The newly identified ORF of the rad1 gene was found to exhibit partial homology to the REC1 gene of Ustilago maydis. These two genes share putative functional similarities in their respective organisms.

引用

页码：155 / 159

页数：5

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