TRISOMY-14 - A RECURRING CYTOGENETIC ABNORMALITY ASSOCIATED WITH MYELOID DISORDERS

被引:11
作者
POIREL, H [1 ]
JONVEAUX, P [1 ]
DANIEL, MT [1 ]
BERGER, R [1 ]
机构
[1] INST GENET MOLEC,INSERM,U301,F-75010 PARIS,FRANCE
关键词
TRISOMY; 14; MYELODYSPLASTIC SYNDROME; APLASTIC ANEMIA; ATYPICAL CHRONIC MYELOID LEUKEMIA;
D O I
10.3109/10428199509056857
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Trisomy 14 as single karyotype aberration was detected in three patients, two with acute myeloblastic leukemia, AML-M2 type, and one with aplastic anemia. These new observations and the 28 previously reported cases confirm that trisomy 14 is a primary non random change, mostly confined to myeloid disorders.
引用
收藏
页码:455 / 457
页数:3
相关论文
共 23 条
[1]  
Heim S., Mitelman F., Numerical chromosome aberrations in human neoplasia, Cancer Genet. Cytogenet., 22, pp. 99-108, (1986)
[2]  
Mitelman F., Catalog of Chromosome Aberrations in Cancer, 4th ed., (1991)
[3]  
Jotterand-Bellomo M., Parlier V., Schmidt P.M., Beris P.H., Cytogenetic analysis of 54 cases of myelodysplastic syndrome, Cancer Genet. Cytogenet., 46, pp. 157-172, (1990)
[4]  
Pinkerton P.H., London B., Dube I.D., Senn J.S., Trisomy 14 in myelodysplastic syndromes, Cancer Genet. Cytogenet., 49, pp. 113-116, (1990)
[5]  
Sole F., Caballin M.R., Coll M.D., Woessner S., Besse C., Palou L., Egozcue J., Isochromosome 14q in myeloid dysplas-tic disorder, Cancer Genet. Cytogenet., 54, pp. 133-134, (1991)
[6]  
Mancini M., Cedrone M., Nanni M., Rondinelli M.B., Petti M.C., De Cuia R., Alimena G., Trisomy 14 in hematologic diseases: another non-random abnormality within myeloid proliferative disorders, Cancer Genet. Cytogenet., 66, pp. 39-42, (1993)
[7]  
Brizard A., Guilhot F., Babin P., Burucoa C., Tanzer J., Huret J.L., Four additional cases of trisomy 14 as the sole anomaly in various haematological malignancies, Leukemia Res., 16, pp. 537-540, (1992)
[8]  
Haas O.A., Jager U., Ambroa P., Pabinger I., Trisomy 14 in refractory anemia with excess of blasts in transformation, Cancer Genet. Cytogenet., 29, pp. 315-318, (1987)
[9]  
Primary, single, autosomal trisomies associated with haematological disorders, Leukemia Res., 16, pp. 841-851, (1992)
[10]  
Nowell P.C., Finan J., Chromosome studies in preleukemic states. IV. Myeloproliferative versus cytopenic disorders, Cancer, 42, pp. 2254-2261, (1978)