NORADRENERGIC PROCESSES INVOLVED IN THE LOCOMOTOR EFFECTS OF ETHANOL

被引：32

作者：

MASON, ST ^{[1
]}

CORCORAN, ME ^{[1
]}

FIBIGER, HC ^{[1
]}

机构：

[1] UNIV BRITISH COLUMBIA, DEPT PSYCHIAT, DIV NEUROL SCI, VANCOUVER V6T 1W5, BC, CANADA

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1979年 / 54卷 / 04期

基金：

英国医学研究理事会;

关键词：

Ethanol; Locomotor activity; Noradrenaline;

D O I：

10.1016/0014-2999(79)90068-2

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Male albino Wistar rats were depleted of forebrain noradrenaline by intracerebral injection of 4 .mu.g of 6-hydorxydopamine into the noradrenaline [norepinephrine] bundles in the mesencephalon. The locomotor response was examined in response to i.p. injection of ethanol. The locomotor stimulation by 0.1 g/kg ethanol was not altered by the lesion, whereas the sedation found in response to 1 g/kg in controls failed to occur in the lesioned rats and instead a stimulation was seen.

引用

页码：383 / 387

页数：5

共 9 条

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