TOPICAL 5-AMINOSALICYLIC ACID - A TREATMENT FOR APHTHOUS ULCERS

被引：26

作者：

COLLIER, PM ^{[1
]}

NEILL, SM ^{[1
]}

COPEMAN, PWM ^{[1
]}

机构：

[1] WESTMINSTER MED SCH & HOSP,DEPT DERMATOL,LONDON SW1,ENGLAND

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1992年 / 126卷 / 02期

关键词：

D O I：

10.1111/j.1365-2133.1992.tb07818.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

A double-blind placebo controlled trial of 5% 5-aminosalicylic acid (5-ASA) cream for the treatment of oral aphthous ulcers was carried out on 22 subjects. The cream or a placebo (11 patients each) was applied to the ulcers three times daily for up to 14 days. Daily discomfort was reduced by half (P < 0.01) and less pain (P < 0.05) was experienced by the treated group. Treatment with 5-ASA shortened healing time (7 vs. 11 days, P < 0.01) and reduced the difficulty in eating (P < 0.05). No significant side-effects were reported. We believe 5-ASA cream to be an effective treatment for aphthous ulcers.

引用

页码：185 / 188

页数：4

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