EXPERIENCE WITH FOSSA RECURRENCE OF RENAL-CELL CARCINOMA

被引:53
作者
ESRIG, D
AHLERING, TE
LIESKOVSKY, G
SKINNER, DG
机构
[1] Department of Urology, School of Medicine, University of Southern California, Los Angeles, CA
关键词
CARCINOMA; RENAL CELL; KIDNEY NEOPLASMS;
D O I
10.1016/S0022-5347(17)37605-X
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
We describe the surgical management and followup of 11 patients with local recurrence of renal cell carcinoma in the renal fossa, 10 of whom demonstrated no evidence of distant metastatic disease at the time of recurrence. Average interval to recurrence was 31 months from nephrectomy, with the majority of patients presenting with symptoms of weight loss, fatigue and lumbar discomfort. A total of 13 resections of recurrent carcinoma was performed with 3 immediate postoperative complications, including a retroperitoneal abscess, jejunal necrosis requiring resection and a duodenal obstruction requiring duodenojejunostomy. There were 2 postoperative deaths, 2 patients died of disseminated disease at 8 and 22 months, and 3 died of causes unrelated to cancer recurrence at 4 months, 6 months and 10 years. Four patients were without disease at a followup of 35, 46, 48 and 211 months. We include in this review a report on 1 patient who maintains a disease-free survival of 17 years after resection of a recurrent spindle cell carcinoma. We conclude that an aggressive surgical approach to recurrent renal cell carcinoma within the renal fossa can produce long-term disease-free survival and is justified when compared to the results reported for chemotherapy.
引用
收藏
页码:1491 / 1494
页数:4
相关论文
共 23 条
[1]   Adenocarcinoma of the kidney with metastasis to the lung - Cured by nephrectomy and lobectomy [J].
Barney, JD ;
Churchill, EJ .
JOURNAL OF UROLOGY, 1939, 42 (03) :269-276
[2]   COMPUTED TOMOGRAPHY IN THE EVALUATION OF POST-NEPHRECTOMY PATIENTS [J].
BERNARDINO, ME ;
DESANTOS, LA ;
JOHNSON, DE ;
BRACKEN, RB .
RADIOLOGY, 1979, 130 (01) :183-187
[3]   TREATMENT OF ADVANCED RENAL-CELL CARCINOMA - TRADITIONAL METHODS AND INNOVATIVE APPROACHES [J].
DEKERNION, JB .
JOURNAL OF UROLOGY, 1983, 130 (01) :2-7
[4]   NATURAL-HISTORY OF METASTATIC RENAL CELL-CARCINOMA - COMPUTER-ANALYSIS [J].
DEKERNION, JB ;
RAMMING, KP ;
SMITH, RB .
JOURNAL OF UROLOGY, 1978, 120 (02) :148-152
[5]  
HALPERIN EC, 1983, CANCER-AM CANCER SOC, V51, P614, DOI 10.1002/1097-0142(19830215)51:4<614::AID-CNCR2820510411>3.0.CO
[6]  
2-J
[7]  
KHOURY S, 1982, RENAL TUMORS
[8]   PROGNOSTIC FACTORS IN METASTATIC RENAL-CARCINOMA [J].
MALDAZYS, JD ;
DEKERNION, JB .
JOURNAL OF UROLOGY, 1986, 136 (02) :376-379
[9]  
MIDDLETON AW, 1980, UROL CLIN N AM, V7, P711
[10]   SURGERY FOR METASTATIC RENAL CELL CARCINOMA [J].
MIDDLETON, RG .
JOURNAL OF UROLOGY, 1967, 97 (06) :973-+