PATIENT EDUCATION FOR SELF-REFERRAL AND ON-DEMAND TREATMENT FOR HERPES-ZOSTER IN LYMPHOMA PATIENTS

被引:13
作者
MAUNG, ZT [1 ]
TAYLOR, PRA [1 ]
ROBINSON, P [1 ]
MOORE, J [1 ]
LUCRAFT, HH [1 ]
EVANS, RGB [1 ]
PROCTOR, SJ [1 ]
机构
[1] ROYAL VICTORIA INFIRM,DEPT HAEMATOL,NEWCASTLE TYNE NE1 4LP,TYNE & WEAR,ENGLAND
关键词
HERPES ZOSTER; LYMPHOMA; ACYCLOVIR; HEALTH EDUCATION;
D O I
10.3109/10428199309067939
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The aim of this study is to evaluate the benefit of educating lymphoma patients in early self-diagnosis of tester and subsequent self-referral for prompt treatment. Each of 337 patients attending an out-patient lymphoma clinic was given an explanatory leaflet and photograph about shingles when they first presented with lymphoma. One to two years following the completion of therapy for lymphoma an assessment was made on these patients using a combination of questionnaire survey and retrospective analysis of case notes. Fifty-six (16.6%) of the study population developed tester following the diagnosis of lymphoma; 29 had had tester prior to the diagnosis (8.6%). There was an increased incidence of herpes tester in patients with Hodgkin's disease as compared to those with non-Hodgkin's lymphoma (P < 0.01). Patients who remembered having received the shingles education leaflets were more likely to make self-referral to hospital for prompt treatment (P < 0.001). Long-term complications, eg post-herpetic neuralgia, were less prevalent in patients presenting to hospital for prompt on-demand therapy, compared to those treated in the community. Education of lymphoma patients regarding awareness of early features of tester is beneficial in preventing complications, but the shingles information episode needs subsequent reinforcement for maximum benefit.
引用
收藏
页码:447 / 452
页数:6
相关论文
共 11 条
[1]  
Jolleys J.V., Treatment of shingles and post-herpetic neuralgia, Br. Med. J., 298, pp. 1537-1538, (1989)
[2]  
Locksley R.M., Flourney N., Sullivan K.M., Meyers J.D., Infection with varicella-zoster virus after marrow transplantation, J. Infect. Dis., 152, pp. 1172-1181, (1985)
[3]  
Perren T.J., Powles R.L., Easton D., Et al., Prevention of herpes zoster in patients by long-term oral acyclo-vir after allogeneic bone marrow transplantation, Am. J. Med., 85, pp. 99-101, (1988)
[4]  
Balfour H.H., Bean B., Laskin O.L., Et al., Acyclovir halts progression of herpes zoster in immunocompro-mised patients, N. Engl. J. Med., 308, pp. 1448-1453, (1983)
[5]  
Proctor S.J., Taylor P., Mackie M.J., Donnan P., Boys R., Lennard A., Prescott R.J., Members of the Scotland and Newcastle Lymphoma Group (SNLG) Therapy Working Party, A numerical prognostic index for clinical use in identification of poor-risk patients with Hodgkin's disease at diagnosis, Leuk. Lymph., 7, pp. 17-20, (1992)
[6]  
Guinee V.F., Guido J.J., Pfalzgraf K.A., Et al., The incidence of herpes zoster in patients with Hodgkins disease: An analysis of prognostic factors, Cancer, 56, pp. 642-648, (1985)
[7]  
Schuchter L.M., Wingard J.R., Piantadosi S., Et al., Herpes zoster infection after autologous bone marrow transplantation, Blood, 74, pp. 1424-1427, (1989)
[8]  
Schimpff S.C., Serpick A., Stoler B., Rumack B., Mellin H., Joseph J.M., Block J., Varicella-zoster infection in patients with cancer, Ann. Int. Med., 76, pp. 241-254, (1972)
[9]  
Jacobson M.A., Berger T.G., Fikrig S., Et al., Acyclovir-resistant varicella zoster virus infection after chronic oral acyclovir therapy in patients with the acquired immunodeficiency syndrome (AIDS), Ann. Int. Med., 112, pp. 187-191, (1990)
[10]  
McKendrick M.W., McGill J.I., Wood M.J., Lack of effect of acyclovir on post-herpetic neuralgia, Br. Med. J., 298, (1989)