CHILDHOOD ECZEMA - DISEASE OF THE ADVANTAGED

被引:192
作者
WILLIAMS, HC
STRACHAN, DP
HAY, RJ
机构
[1] UNITED MED & DENT SCH GUYS & ST THOMAS HOSP,GUYS HOSP,ST JOHNS INST DERMATOL,LONDON SE1 9RT,ENGLAND
[2] ST GEORGE HOSP,SCH MED,DEPT PUBL HLTH SCI,LONDON SW17 0RE,ENGLAND
关键词
D O I
10.1136/bmj.308.6937.1132
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective-To determine whether the increased prevalence of childhood eczema in advantaged socioeconomic groups is due to increased parental reporting. Design-Comparison of parental reports of eczema with visible eczema recorded by medical officers during a detailed physical examination. Setting-National birth cohort study. Subjects-8279 children from England, Wales, and Scotland born during 3-9 March 1958 and followed up at the ages of 7, 11, and 16. Main outcome measures-Prevalence of eczema according to parental report compared with medical officer's examination at the ages of 7, 11, and 16. Results-Prevalence of both reported and examined eczema increased with rising social class at the ages of 7, 11, and 16 years. The point prevalence of examined eczema at age 7 was 4.8%, 3.6%, 3.6%, 2.4%, 2.2%, and 2.4% in social classes I, II, III nonmanual, III manual, TV, and V respectively (chi(2) value for linear trend 12.6, P < 0.001). This trend persisted after adjustment for potential confounders such as region and family size and was not present for examined psoriasis or acne. Conclusions-Eczema is more prevalent among British schoolchildren in social classes I and II than those in lower classes, Exposures associated with social class are probably at least as important as genetic factors in the expression of childhood eczema.
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页码:1132 / 1135
页数:4
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