INCREASED SUSCEPTIBILITY OF PSEUDOMONAS-AERUGINOSA TO CIPROFLOXACIN IN THE PRESENCE OF VANCOMYCIN

被引:14
作者
DAY, CA
MARCEAUDAY, ML
DAY, DF
机构
[1] ST JOSEPHS ACAD,BATON ROUGE,LA 70803
[2] LOUISIANA STATE UNIV,CTR ADV MICROSTRUCT & DEVICES,BATON ROUGE,LA 70803
[3] LOUISIANA STATE UNIV,AUDUBON SUGAR INST,SUGAR STN,BATON ROUGE,LA 70803
[4] LOUISIANA STATE UNIV,AGR EXPT STN,BATON ROUGE,LA 70803
关键词
D O I
10.1128/AAC.37.11.2506
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Vancomycin in combination with ciprofloxacin exhibited synergy against 7 of 10 strains of Pseudomonas aeruginosa. MICs for the microbial strains used in this study ranged from 0.0325 to 3.0 mug/ml for ciprofloxacin and from 23.5 to >188 mug/ml for vancomycin. Combinations of these antibiotics, tested in a checkerboard pattern, gave fractional inhibitory concentrations of 0.5 or less for 7 of the 10 strains tested.
引用
收藏
页码:2506 / 2508
页数:3
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