SYNTHETIC VACCINES .1. SYNTHESIS OF MULTIVALENT TN ANTIGEN CLUSTER-LYSYLLYSINE CONJUGATES

被引：25

作者：

TOYOKUNI, T ^{[1
]}

DEAN, B ^{[1
]}

HAKOMORI, S ^{[1
]}

机构：

[1] UNIV WASHINGTON, SEATTLE, WA 98195 USA

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 19期

关键词：

D O I：

10.1016/S0040-4039(00)94669-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Monomer, dimer, and trimer of Tn antigen (GalNAcα1→O-Ser) were coupled to L-lysyllysine to construct multivalent and clustering structures of Tn antigen. The method has made it possible to provide pertinent carbohydrate antigens for the development of synthetic vaccines against tumors. © 1990.

引用

页码：2673 / 2676

页数：4

共 29 条

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