PRESENCE OF IMMUNOREACTIVE ENDOTHELIN IN HUMAN-MILK

被引：35

作者：

LAM, HC ^{[1
]}

TAKAHASHI, K ^{[1
]}

GHATEI, MA ^{[1
]}

BLOOM, SR ^{[1
]}

机构：

[1] HAMMERSMITH HOSP,ROYAL POSTGRAD MED SCH,DEPT MED,FRANCIS FRASER LAB,2ND FLOOR,DU CANE RD,LONDON W12 0NN,ENGLAND

来源：

FEBS LETTERS | 1990年 / 261卷 / 01期

关键词：

Chromatography; Endothelin; Human milk; Radioimmunoassay;

D O I：

10.1016/0014-5793(90)80666-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Endothelin-like immunoreactivity was detected in human milk at a concentration of 6.8 ± 1.6 pmol l(mean ± SEM; n = 16) using a highly sensitive radioimmunoassay. Gel filtration and fast protein liquid chromatography (FPLC) verified the identity of the endothelin. FPLC revealed 4 peaks, one eluting just after the void volume, and the other three in the positions of endothelin-1, -2, and -3, respectively. © 1990.

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页码：184 / 186

页数：3

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