TREATMENT OF ACUTE EXACERBATIONS OF CHRONIC OBSTRUCTIVE AIRWAYS DISEASE - A COMPARISON OF AMOXYCILLIN AND CIPROFLOXACIN

被引：36

作者：

BASRAN, GS ^{[1
]}

JOSEPH, J ^{[1
]}

ABBAS, AMA ^{[1
]}

HUGHES, C ^{[1
]}

TILLOTSON, GS ^{[1
]}

机构：

[1] BAYER UK LTD,NEWBURY RG13 1JA,ENGLAND

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1990年 / 26卷

关键词：

D O I：

10.1093/jac/26.suppl_F.19

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Ciprofloxacin and amoxycillin were compared in the treatment of acute exacerbations of chronic obstructive airways disease. One hundred and forty patients were evaluable for overall outcome; 60 patients' sputum specimens yielded positive bacteriological cultures. The predominant pathogens were HaemophUus influenzae (43.3%) and Streptococcus pneumoniae (25.0%). Both regimens were safe and produced few adverse effects. An independent observer judged ciprofloxacin to produce a 91.8% success rate (complete success 21.9%; partial success 69.9%) whilst a 73.1% rate (complete success 10.4%; partial success 62.7%) was seen with amoxycillin. © 1990 The British Society for Antimicrobial Chemotherapy.

引用

页码：19 / 24

页数：6

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