MAPPING THE ELECTROSTATIC POTENTIAL OF MUSCARINIC AND NICOTINIC AGONISTS WITH ARTIFICIAL NEURAL NETWORKS

被引：28

作者：

GASTEIGER, J ^{[1
]}

LI, XZ ^{[1
]}

机构：

[1] TECH UNIV MUNICH,INST ORGAN CHEM,D-85747 GARCHING,GERMANY

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1994年 / 33卷 / 06期

关键词：

D O I：

10.1002/anie.199406431

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Distinct similarities can be detected with artificial neural networks between molecules that bind to the muscarinic receptors (e.g. 1 and 2) and between molecules that bind to nicotinic receptors (e.g. 3 and 4). Furthermore such networks highlight differences between molecules that bind at these two different receptors. (Figure Presented.) Copyright © 1994 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：643 / 646

页数：4

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