STRUCTURE OF ALKALINE METMYOGLOBIN-XENON COMPLEX

被引：49

作者：

SCHOENBORN, BP

机构：

[1] Biology Department, Brookhaven National Laboratory Upton

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1969年 / 45卷 / 02期

关键词：

D O I：

10.1016/0022-2836(69)90106-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Structural changes of alkaline metmyoglobin compared to neutral metmyoglobin have been determined by a three-dimensional X-ray diffraction analysis. Alkaline metmyoglobin crystals proved, however, to be somewhat unstable under X-irradiation. Exposure of crystals to xenon stabilized them thus permitting the necessary extended X-ray exposures. Structural changes were determined by inspection of difference electron density maps with subsequent refinement by a difference least-squares method. The results show two xenon binding sites in addition to a number of structural rearrangements. © 1969.

引用

页码：297 / +

页数：1

共 14 条

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