INVITRO ACTIVITIES OF NEW MACROLIDES AND RIFAPENTINE AGAINST BRUCELLA SPP

被引：26

作者：

GARCIARODRIGUEZ, JA

BELLIDO, JLM

FRESNADILLO, MJ

TRUJILLANO, I

机构：

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1993年 / 37卷 / 04期

关键词：

D O I：

10.1128/AAC.37.4.911

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We have tested the in vitro activities of streptomycin, rifampin, tetracyclines, trimethoprim-sulfamethoxazole, erythromycin, four new macrolides (roxithromycin, azithromycin, clarithromycin, and dirithromycin), and rifapentine against 62 strains of Brucella spp. Azithromycin and clarithromycin were, respectively, eight- and twofold more active than erythromycins (MIC for 90% of strains = 2, 8, and 16 mug/ml, respectively). The activity of rifapentine was similar to that of rifampin (MIC for 90% of strains = 1 mug/ml).

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页码：911 / 913

页数：3

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