1ST-TRIMESTER UTEROPLACENTAL AND FETAL BLOOD-FLOW VELOCITY WAVE-FORMS IN NORMALLY DEVELOPING FETUSES - A LONGITUDINAL-STUDY

被引：21

作者：

VANZALENSPROCK, MM

VANVUGT, JMG

COLENBRANDER, GJ

VANGEIJN, HP

机构：

[1] Division of Maternal-Fetal Medicine and Prenatal Diagnosis, Department of Obstetrics and Gynecology, Free University Hospital, De Boelelaan 1117, Postbox 7057, Amsterdam

来源：

ULTRASOUND IN OBSTETRICS & GYNECOLOGY | 1994年 / 4卷 / 04期

关键词：

1ST-TRIMESTER DOPPLER; NORMAL FETUSES; VITELLINE ARTERY;

D O I：

10.1046/j.1469-0705.1994.04040284.x

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

Our objectives were to obtain a complete overview of uteroplacental and fetal hemodynamics early in pregnancy and to record flow velocity waveforms in the vitelline artery using color Doppler equipment. Flow velocity waveforms were recorded in 18 uneventful pregnancies between 6 and 16 weeks of gestation. Doppler recordings were made of the left and right uterine and spiral arteries from 6 weeks of gestation onwards. Recordings of the umbilical artery, fetal aorta and fetal cerebral arteries started in weeks 7, 8 and 9, respectively. Where possible, the vitelline arteries were also recorded. The resistance and pulsatility indices and 95% confidence intervals for predictions were calculated. For the uterine and spiral arteries, characteristics of the waveforms were assessed. The resistance index of both uterine and spiral arteries gradually decreased with advancing pregnancy. For the umbilical artery, aorta and cerebral artery, the earliest possible Doppler recordings and characteristics of the waveforms were established. The pulsatility index of the umbilical arteries and fetal aorta showed a sharp decrease towards the 16th week. The pulsatility index of the fetal cerebral artery showed only a mild decrease towards week 16. In a longitudinal analysis, there were significant changes of the resistance and pulsatility indices for each patient. In the vitelline artery, recordings were possible in eight out of 18 fetuses, and only in weeks 7 and 8 of gestation. The pulsatility index showed a wide range and was not dependent on menstrual age. Knowledge of the normal flow velocity waveforms in the maternal uteroplacental and fetal circulations early in pregnancy may lead to a better understanding of physiological mechanisms.

引用

页码：284 / 288

页数：5

共 11 条

[1] Deutinger J., Rudelstorfer R., Bernaschek G., Vaginosonographic velocimetry of both main uterine arteries by visual vessel recognition and pulsed Doppler method during pregnancy, Am. J. Obstet. Gynecol., 159, pp. 1072-1076, (1988)
[2] Jaffe R., Warsof S.L., Transvaginal color Doppler imaging in the assessment of utero-placental blood flow in the normal first trimester pregnancy, Am. J. Obstet. Gynecol., 164, pp. 781-785, (1991)
[3] Kaminopetros P., Higueras M.T., Nicolaides K.H., Doppler study of uterine artery blood flow: Comparison of findings in the first and second trimester of pregnancy, Fetal Diagn. Ther., 6, pp. 58-64, (1991)
[4] Jurkovic D., Jauniaux E., Kurjak A., Hustin J., Campbell S., Nicolaides K.H., Transvaginal color Doppler assessment of the uteroplacental circulation in early pregnancy, Obstet. Gynecol., 11, pp. 365-369, (1991)
[5] Stabile I., Grudzinskas J., Campbell S., Doppler ultrasonographic evaluation of abnormal pregnancies in the first trimester, J. Clin. Ultrasound, 18, pp. 497-501, (1990)
[6] Jauniaux E., Jurkovic D., Campbell S., In vivo investigations of the anatomy and the physiology of early human placental circulations, Ultrasound Obstet. Gynecol., 1, pp. 435-445, (1991)
[7] Jauniaux E., Jurkovic D., Campbell S., Hustin J., Doppler ultrasonographic features of the developing placental circulation: Correlation with anatomic findings, Am. J. Obstet. Gynecol., 166, pp. 585-587, (1992)
[8] Arduini D., Rizzo G., Umbilical artery velocity waveforms in early pregnancy: A transvaginal color Doppler study, J. Clin. Ultrasound, 19, pp. 335-339, (1991)
[9] Wladimiroff J.W., Huisman T.W.A., Stewart P.A., Intracerebral aortic and umbilical artery flow velocity waveforms in the late-first trimester fetus, Am. J. Obstet. Gynecol., 166, pp. 46-49, (1992)
[10] Huisman T.W.A., Steward P.A., Wladimiroff J.W., Doppler assessment of the normal early fetal circulation, Ultrasound Obstet. Gynecol., 2, pp. 300-305, (1992)

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