TO STRAINS OF THEILERS VIRUSES CAUSE SLOW VIRUS-LIKE INFECTIONS IN MICE

被引：40

作者：

LIPTON, HL

DALCANTO, MC

机构：

[1] NORTHWESTERN UNIV, SCH MED, DEPT NEUROL, CHICAGO, IL 60611 USA

[2] NORTHWESTERN UNIV, SCH MED, DEPT PATHOL NEUROPATHOL, CHICAGO, IL 60611 USA

来源：

ANNALS OF NEUROLOGY | 1979年 / 6卷 / 01期

关键词：

D O I：

10.1002/ana.410060106

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Intracerebral inoculation of mice with tissue culture–adapted TO strains of Theiler's mouse encephalomyelitis viruses results in a clinical disease consisting of spastic paralysis due to demyelination after a lengthy incubation period. Thus, in effect, these ordinary picornaviruses are capable of causing a slow infection in their natural host, the mouse. In addition, through the use of tissue culture–adapted virus stocks, virus content in mouse tissues now can be accurately quantified by standard plaque assay. Copyright © 1979 American Neurological Association

引用

页码：25 / 28

页数：4

共 21 条

[1]

DALCANTO MC, 1977, AM J PATHOL, V88, P497

[2]

DALCANTO MC, 1975, LAB INVEST, V33, P626

[3] RISK OF MULTIPLE SCLEROSIS ACCORDING TO AGE AT IMMIGRATION TO SOUTH AFRICA [J].