CHANNEL-TYPE MOLECULAR-STRUCTURES .2. SYNTHESIS OF BOUQUET-SHAPED MOLECULES BASED ON A BETA-CYCLODEXTRIN CORE

被引:61
作者
CANCEILL, J [1 ]
JULLIEN, L [1 ]
LACOMBE, L [1 ]
LEHN, JM [1 ]
机构
[1] COLL FRANCE,CHIM INTERACT MOLEC LAB,11 PL MARCELIN BERTHELOT,F-75005 PARIS,FRANCE
关键词
D O I
10.1002/hlca.19920750315
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new series of channel-type molecules presenting the features of potential transmembrane structures is described. They result from the grafting of amphiphilic side chains on a beta-cyclodextrin derivative 3 that constitutes the organizing core. They belong to the 'bouquet' family (B). Compounds bearing poly(oxyethylene) side chains, B(CD)O 16 and 17, and their polymethylene analogues B(CD)C 18 and 19, were synthesized. The properties investigated emphasize the suitability of such molecules to be incorporated into lipid bilayer membranes.
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页码:791 / 812
页数:22
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