A KINETIC ISOTOPE EFFECT IN PHOTOREACTIVATION OF UV-INACTIVATED TOBACCO MOSAIC VIRUS RNA

被引:9
作者
EVANS, NA
MCLAREN, AD
机构
[1] College of Agricultural Sciences, University of California, Berkeley, California
关键词
D O I
10.1111/j.1751-1097.1969.tb07288.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Abstract— Inactivation of tobacco mosaic virus RNA (TMV‐RNA) by u.v. radiation is slower in D2O than in H2O, and TMV‐RNA which has been inactivated in D2O is photoreactivated faster (on Pinto bean) than TMV‐RNA which has been inactivated in H2O. The maximum amount of photoreactivation is unaffected by the solvent, H2O or D2O, present during irradiation. These deuterium isotope effects for inactivation and photoreactivation suggest that pyrimidine hydrates are photoreactivable lesions on Pinto bean. Copyright © 1969, Wiley Blackwell. All rights reserved
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页码:243 / &
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