RBE OF 14-MEV NEUTRONS - OBSERVATIONS ON COLONY-FORMING UNITS IN MOUSE BONE-MARROW

被引:16
作者
DUNCAN, W
GREENE, D
HOWARD, A
MASSEY, JB
机构
[1] Paterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester
[2] Christie Hospital and Holt Radium Institute, Manchester
来源
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY AND RELATED STUDIES IN PHYSICS CHEMISTRY AND MEDICINE | 1969年 / 15卷 / 05期
关键词
D O I
10.1080/09553006914550681
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
The effectiveness of 14 MeV neutrons from the D-T reaction was compared with that of 60Co γradiation in killing mouse bone-marrow cells capable of forming spleen colonies after transfer to lethally-irradiated isologous recipients. The survival curves for the two radiations were found to have the same extrapolation number (1·38 ± 0·15). The D0 for neutrons was 63·7 ± 3·3 rads, and for γrays was 106 ± 5·1 rads. The ratio of these values gave the relative biological effectiveness (RBE) which, for the comparison 14 MeV neutrons/60Co γ is 1·67 ± 0·06. © 1969 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码:397 / &
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