IDENTIFICATION OF THE PORCINE PARAMYXOVIRUS LPMV MATRIX PROTEIN GENE - COMPARATIVE SEQUENCE-ANALYSIS WITH OTHER PARAMYXOVIRUSES

被引：30

作者：

BERG, M ^{[1
]}

SUNDQVIST, A ^{[1
]}

MORENOLOPEZ, J ^{[1
]}

LINNE, T ^{[1
]}

机构：

[1] SWEDISH UNIV AGR SCI,CTR BIOMED,DEPT VET MICROBIOL MOLEC VIROL,S-75123 UPPSALA,SWEDEN

来源：

JOURNAL OF GENERAL VIROLOGY | 1991年 / 72卷

关键词：

D O I：

10.1099/0022-1317-72-5-1045

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The complete nucleotide sequence of the gene encoding the matrix protein (M) of the porcine paramyxovirus LPMV has been determined. The gene is 1376 nucleotides long including 5' and 3' non-coding sequences with a protein-coding sequence of 1107 nucleotides. The deduced protein, containing 369 amino acids with a calculated M(r) of 41657, is hydrophobic overall with a net positive charge of +17.5. Comparative sequence analysis revealed high amino acid homology to other paramyxovirus M proteins, with the highest degree of identity (46%) with the human mumps virus. This is strong evidence that the porcine paramyxovirus LPMV is a genuine member of the paramyxovirus genus.

引用

页码：1045 / 1050

页数：6

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