USEFULNESS OF TAURINE IN CHRONIC CONGESTIVE-HEART-FAILURE AND ITS PROSPECTIVE APPLICATION

被引：102

作者：

AZUMA, J

SAWAMURA, A

AWATA, N

机构：

[1] Third Department of Internal Medicine, Osaka University Medical School, Osaka

来源：

JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION | 1992年 / 56卷 / 01期

关键词：

TAURINE; COENZYME-Q10; CONGESTIVE HEART FAILURE; DOUBLE-BLIND STUDY;

D O I：

10.1253/jcj.56.95

中图分类号：

N09 [自然科学史]; B [哲学、宗教];

学科分类号：

01 ; 0101 ; 010108 ; 060207 ; 060305 ; 0712 ;

摘要：

We compared the effect of oral administration of taurine (3 g/day) and coenzyme Q10 (CoQ10) (30 mg/day) in 17 patients with congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy, whose ejection fraction assessed by echocardiography was less than 50%. The changes in echocardiographic parameters produced by 6 weeks of treatment were evaluated in a double-blind fashion. In the taurine-treated group significant treatment effect was observed on systolic left ventricular function after 6 weeks. Such an effect was not observed in the CoQ10-treated group.

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页码：95 / 99

页数：5

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