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ISOLATION AND CHARACTERIZATION OF 3 MICROSATELLITE MARKERS IN THE PROXIMAL LONG ARM OF THE HUMAN X-CHROMOSOME

被引：6
作者：
LINDSAY, S
CURTIS, ARJ
ROUSTAN, P
KAMAKARI, S
THISELTON, DL
STEPHENSON, A
BHATTACHARYA, SS
机构：
[1] UNIV NEWCASTLE UPON TYNE,DIV HUMAN GENET,MOLEC GENET UNIT,NEWCASTLE TYNE NE1 7RU,TYNE & WEAR,ENGLAND
[2] INST OPHTHALMOL,DEPT MOLEC GENET,LONDON EC1V 9EL,ENGLAND
来源：
GENOMICS | 1993年 / 17卷 / 01期
基金：
英国惠康基金;
关键词：
D O I：
10.1006/geno.1993.1303
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Three microsatellites have been identified in cosmids from the human X chromosome. The cosmids have been assigned locus members DXS554, DXS559, and DXS566 and have been localized to Xq12-q13 (DXS554 and DXS559) and Xq13 (DXS566). In addition, they have been genetically mapped in relation to the androgen receptor (AR), phosphoglycerate kinase (PGK1) loci in the proximal long arm. Genetically, the localization of microsatellites at DXS554 and DXS559 is indistinguishable from PGK1, whereas that at DXS559 maps between AR and PGK1, close to PGK1P1. DXS566 is identical to the independently identified DXS441 marker. These markers should be useful for physical and genetic mapping in this region. © 1993 Academic Press. All rights reserved.
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页码：208 / 210
页数：3
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