A SYNTHESIS OF (-)-INDOLACTAM-V

被引：47

作者：

SEMMELHACK, MF

RHEE, H

机构：

[1] Department of Chemistry, Princeton University, Princeton

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 09期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(00)60300-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(-)-Indolactam V (1) was synthesized in 14 steps from 2,6-dinitrotoluene in 15% overall yield via enantiospecific S(N)2 displacement of a chiral triflate with the 4-amino group of a 4-aminoindole and coupling of 3-bromomethyl indole with Schollkopf's asymmetric bislactim ether.

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页码：1395 / 1398

页数：4

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