ACUTE TOXICITY OF ALKYL (1-PHENYLSULFONYL)CYCLOALKANE-CARBOXYLATES TO DAPHNIA-MAGNA AND QUANTITATIVE STRUCTURE - ACTIVITY RELATIONSHIPS

被引：14

作者：

HE, YB ^{[1
]}

WANG, LS ^{[1
]}

LIU, ZT ^{[1
]}

ZHANG, Z ^{[1
]}

机构：

[1] NANJING UNIV,DEPT CHEM,NANJING 210008,PEOPLES R CHINA

来源：

CHEMOSPHERE | 1995年 / 31卷 / 02期

关键词：

D O I：

10.1016/0045-6535(95)00129-V

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Acute toxicities of alkyl (l-phenylsulfonyl) cycloalkane-carboxylates toc Daphnia magna are correlated by linear solvation energy relationships, The biological response, as a function of toxicant properties, is given by log 1/LC(50)(mol/L) = 2.08(0.24) + 1.90(0.11)V-1/100 - 1.20(0.24)beta n = 22 r = 0.964 sd = 0.085 log 1/EC(50)(mol/L) = 2.45(0.27) + 1.91(0.13)V-1/100 - 1.24(0.27)beta n = 22 r = 0.955 sd = 0.096 where V-1 is the intrinsic solute molecular volume, beta is the solvatochromic parameter that measures hydrogen bond basicity of the toxicant. The predicted values with above two equations are close to observed ones, The above equations also provide quantitative information on the factors affecting toxicity of alkyl (l-phenylsulfonyl) cycloalkane-carboxylates.

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页码：2739 / 2746

页数：8

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