CONTROL OF OIL-IN-WATER EMULSION CONSISTENCY USING MIXED EMULSIFIERS

被引:27
作者
BARRY, BW
机构
[1] Department of Pharmaceutical Technology, School of Pharmacy, Porstmouth College of Technology, Portsmouth
关键词
D O I
10.1111/j.2042-7158.1969.tb08307.x
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Mixtures of emulsifiers of the surfactant‐fatty alcohol type are widely used to stabilize oil‐in‐water emulsions and to alter their consistency from fluid to semi‐solid. A mechanism, involving the formation of a viscoelastic network in the continuous phase, is proposed to explain this self‐bodying action. Evidence has been adduced from published data on a variety of systems. Support for this concept is also provided by the results obtained from a concentric cylinder study of the rheology of liquid paraffin in water emulsions containing a fixed concentration of cetostearyl alcohol and varying amounts of polyoxyethylene sorbitan monooleate, cetomacrogol 1000, sodium dodecyl sulphate or cetrimide. 1969 Royal Pharmaceutical Society of Great Britain
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页码:533 / &
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