MODIFICATION OF HISTONES IMMEDIATELY FOLLOWING SYNTHESIS

被引：21

作者：

SEALY, L

CHALKLEY, R

机构：

[1] Department of Biochemistry, College of Medicine, University of Iowa, Iowa City

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1979年 / 197卷 / 01期

关键词：

D O I：

10.1016/0003-9861(79)90221-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The acetylation of newly synthesized histones has been studied by exploiting the ability of sodium butyrate to inhibit deacetylation. Upon arrival in the nucleus a significant fraction of histones H2a, H2b, and H3 is in the parental unmodified form. In contrast histone H4 first appears primarily in the diacetylated form. During an ensuing 135 min the diacetylated H4 is slowly further modified. © 1979.

引用

页码：78 / 82

页数：5

共 24 条

[1] PHOSPHORYLATION OF LYSINE-RICH HISTONES THROUGHOUT CELL-CYCLE [J].