(6R)-5,6,7,8-TETRAHYDRO-ALPHA-BIOPTERIN AFFECTS VASOPRESSIN AND OXYTOCIN RELEASE FROM RAT NEUROINTERMEDIATE LOBE INVITRO

被引：1

作者：

CIOSEK, J

GUZEK, JW

机构：

[1] Department of Pathophysiology, University School of Medicine, Łódź

来源：

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY | 1990年 / 95卷 / 03期

关键词：

Biopterines; Neurohypophysis; Oxytocin; Vasopressin;

D O I：

10.1055/s-0029-1210967

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Incubation of neurointermediate lobes in Locke's solution containing 0.13 μmol · l−1 (6R)-5,6,7,8-tetrahydro-alpha-biopterin dihydrochloride (THB4) resulted in an inhibition of bioassayed vasopressin secretion and in an increase of that of oxytocin both under resting conditions as well as during depolarization due to excess potassium.It is suggested that some events related to THB4and localized in the neural lobe are involved in the mechanism of vasopressin and oxytocin release. © 1990, J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart, New York. All rights reserved.

引用

页码：287 / 291

页数：5

共 23 条

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